ethyl 6-chloro-4-ethoxypyridine-3-carboxylate

ethyl 6-chloro-4-ethoxypyridine-3-carboxylate - Names and Identifiers

Name	ethyl 6-chloro-4-ethoxypyridine-3-carboxylate
Synonyms	Ethyl 6-chloro-4-ethoxynicotinate ethyl 6-chloro-4-ethoxypyridine-3-carboxylate 6-chloro-4-ethoxy-3-pyridinecarboxylic acid ethyl ester 6-Chloro-4-ethoxypyridine-3-carboxylic acid ethyl ester 3-pyridinecarboxylic acid, 6-chloro-4-ethoxy-, ethyl ester Ethyl 6-chloro-4-ethoxypyridine-3-carboxylate, 2-Chloro-4-ethoxy-5-(ethoxycarbonyl)pyridine
CAS	40296-47-7
EINECS	604-604-1
InChI	InChI=1/C10H12ClNO3/c1-3-14-8-5-9(11)12-6-7(8)10(13)15-4-2/h5-6H,3-4H2,1-2H3

ethyl 6-chloro-4-ethoxypyridine-3-carboxylate - Physico-chemical Properties

Molecular Formula	C10H12ClNO3
Molar Mass	229.66
Density	1.211±0.06 g/cm3 (20 ºC 760 Torr)
Melting Point	73-74℃ (ligroine )
Boling Point	313.9°C at 760 mmHg
Flash Point	143.7°C
Vapor Presure	0.000481mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.512

ethyl 6-chloro-4-ethoxypyridine-3-carboxylate - Risk and Safety

Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
HS Code	29333990

ethyl 6-chloro-4-ethoxypyridine-3-carboxylate - Introduction

Ethyl is an organic compound with the chemical formula C11H12ClNO3. It is a yellow to light orange solid. The following is a detailed description of the properties, uses, preparation and safety information of the compound:

Nature:
-Appearance: Yellow to light orange solid
-Molecular weight: 245.67g/mol
-Melting point: 82-85°C
-Boiling point: 364.9°C
-Solubility: Insoluble in water, soluble in organic solvents such as alcohol and ether

Use:
- ethyl l As an organic synthesis intermediate, it is commonly used in the synthesis of other organic compounds. It has a wide range of applications in drug development, pesticide synthesis and other organic synthesis reactions.

Preparation Method:
- ethyl l can generate 4-ethoxy-6-chloropyridine by reacting chloropyridine with ethyl acetate, and then react with chloroformic acid to obtain the target compound.
-The reaction steps are as follows:
1. reacting chloropyridine with ethyl acetate under alkaline conditions to produce 4-ethoxy-6-chloropyridine;
2. React 4-ethoxy-6-chloropyridine with chloroformic acid under alkaline conditions to obtain ethyl l.

Safety Information:
- ethyl l may be irritating to eyes, skin and respiratory tract. Care should be taken to avoid contact with skin, eyes and use.
-Avoid inhaling dust and gas, and ensure that you operate in a well-ventilated place.
-For accidental exposure or inhalation, seek medical attention immediately and show the compound's safety data sheet to the doctor.

Last Update：2024-04-09 02:00:45